OMNARIS (ciclesonide) Nasal Spray is for the treatment of nasal allergy symptoms associated with seasonal allergic rhinitis (seasonal allergies) in adults and children 6 years of age and older, and with perennial allergic rhinitis (year-round allergies) in adults and adolescents 12 and older.

Important Safety Information

Patients using corticosteroid drugs that weaken the immune system are more susceptible to infection and should avoid exposure to chickenpox or measles. If you have tuberculosis, eye herpes, or untreated infections of any kind, speak to your doctor before using OMNARIS. Yeast infections of the nose and throat may occur.

Patients who have recently had an ulcer in the nose, trauma to the nose or nasal surgery should not use OMNARIS until healing has occurred. Rare instances of nasal irritation and eye problems have been reported following the use of nasal steroids. Talk with your doctor if you have a history of eye problems or experience a change in vision.

Patients taking higher doses of a nasal steroid than recommended, or certain other at-risk individuals, may experience symptoms of a hormonal imbalance, including very rarely changes in menstruation, acne, and weight gain. Like all steroid nasal sprays, OMNARIS may cause slowed growth in children. The growth of children using OMNARIS should be monitored routinely by a healthcare professional.

The most common side effects that may occur with OMNARIS are headache, nosebleed, sore throat and ear pain.

The health information contained on this website is provided for educational purposes only and is not intended to replace discussions with a healthcare professional. The product discussed on this site may have different product labeling in different countries. All decisions regarding patient care must be made with a healthcare professional, considering the unique characteristics of the patient.

For more information, please see the OMNARIS Full Prescribing Information and the OMNARIS Patient's Instructions for Use.

OMNARIS is available by prescription. Ask your healthcare professional if OMNARIS is right for you. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

The health information contained on this website is provided for educational purposes only and is not intended to replace discussions with a healthcare professional. This site is intended for U.S. residents only. The product discussed on this site may have different product labeling in different countries. All decisions regarding patient care must be made with a healthcare professional, considering the unique characteristics of the patient.

Indication for ALVESCO
ALVESCO is for the long-term treatment of asthma as preventative therapy in adults and adolescents 12 years of age and older.

Important Safety Information about ALVESCO
ALVESCO is NOT a rescue inhaler and should not be used for relief of sudden symptoms of shortness of breath during an asthma attack. Use a fast-acting rescue medicine (such as a levalbuterol inhaler) to relieve sudden symptoms if you have an asthma attack. You should contact your healthcare professional if an asthma attack does not respond to your rescue medicine or you need to use your rescue medicine more often than usual.

You should not use ALVESCO if you are allergic to ciclesonide or any of the ingredients in ALVESCO. Rare cases of severe allergic reactions, including swelling of the lips, tongue and throat, have been reported.

It is important to take ALVESCO regularly, as prescribed. Do not stop treatment even if you are feeling better, unless told to do so by your healthcare professional. You should contact your healthcare professional if your symptoms do not improve after 4 weeks, or if your condition worsens at any time during treatment. DO NOT inhale more doses or use your ALVESCO inhaler more often than you have been directed.

Yeast infections of the mouth and throat (thrush) have occurred in some ALVESCO patients. Rinse your mouth after you inhale each dose of ALVESCO. If you develop a yeast infection, it should be treated by a healthcare professional. Patients taking ALVESCO are at a possible increased risk of infection due to a weakened immune system that may occur when taking a steroid medicine. Tell your healthcare professional if you have had tuberculosis (TB) or any other infections before or while using ALVESCO, or if you are exposed to chickenpox or measles.

If you took an oral (by mouth) steroid previously and are having the dose decreased, or you have been switched to ALVESCO from an oral steroid, tell your healthcare professional right away about any symptoms such as feeling tired or exhausted, weakness, nausea, vomiting, or symptoms of low blood pressure (such as dizziness or faintness). These may be symptoms of a potentially life-threatening condition in which your body does not produce enough natural steroids.

Using inhaled steroid medicines for a long time may put you at greater risk for decreased bone mass (which can cause bones to become weaker). Inhaled corticosteroids including ALVESCO may cause slowed growth in children and adolescents. Your healthcare professional should monitor your bone health and the growth of children and adolescents taking ALVESCO.

As with other inhaled asthma medicines, bronchospasm (a sudden squeezing of the airways) can occur, with wheezing, right after you inhale your dose of ALVESCO. If this happens, stop using ALVESCO and use a rescue medicine right away, such as levalbuterol. You should also inform your healthcare professional right away so that your asthma medicine can be re-evaluated.

The most common side effects with ALVESCO include headache, pain or irritation of the nose and throat, sinus infection, upper respiratory infection (such as the common cold), joint pain, stuffy nose, leg pain, and back pain.

Indication for XOPENEX HFA
XOPENEX HFA® is indicated for the treatment or prevention of bronchospasm in adults, adolescents, and children 4 years of age and older with reversible obstructive airway disease.

Important Safety Information about XOPENEX HFA
Like other inhaled beta-agonists, XOPENEX HFA can produce a narrowing of the airways called paradoxical bronchospasm, which may be life-threatening.

While you are using XOPENEX HFA Inhalation Aerosol, other inhaled drugs and asthma medications should be taken only as directed by your healthcare professional.

XOPENEX HFA can cause significant heart-related side effects, such as an increase in pulse, blood pressure and/or related symptoms. If you have a heart condition, your healthcare professional will determine if XOPENEX HFA is right for you.

Use as directed by your healthcare professional. Deaths have been reported with similar inhaled medications in asthma patients who use too much medication.

Hypersensitivity reactions (severe allergic reactions) may occur immediately after taking XOPENEX HFA. If you experience itching, areas of skin swelling (angioedema), skin rash, or narrowing of the airways, these may be signs of a hypersensitivity reaction. Seek immediate medical attention if this happens.

If you find that treatment becomes less effective, your symptoms become worse and/or you need to use the product more frequently than usual, you should seek medical attention immediately.

If you currently have, or have had, a history of the following conditions, your healthcare professional will evaluate you to decide if XOPENEX HFA is right for you:

• heart disease (e.g., reduced heart circulation, high blood pressure, and irregular heartbeat)
• seizures
• high levels of thyroid hormone
• diabetes
• reactions to medications similar to XOPENEX HFA

In adolescents and adults, side effects may include pain, dizziness, asthma, sore throat, and runny nose. The side effects of XOPENEX HFA may depend on the number of puffs used within a given period of time. Do not exceed the dosage prescribed by your healthcare professional.